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Exploring the activity and the essentiality of the putative Δ6-desaturase in the procyclic and bloodstream forms of <i>Trypanosoma brucei</i>

2023-11-24

Abstract excerpt

<h4> Abstract </h4> Trypanosomatids have been shown to possess an exclusive and finely regulated biosynthetic pathway for de novo synthesis of fatty acids (FAs) and particularly of polyunsaturated fatty acids (PUFAs). The key enzymes for the process of unsaturation are known as desaturases. In this work, we explored the biocatalytic activity of the putative Δ6-desaturase (Tb11.v5.0580) in the native organism T...

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Literature Corpus work
8ee8269b-6fc8-5dda-a7ee-9f8418fed92d
DOI
10.1101/2023.11.23.568515
Open publication

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Exploring the activity and the essentiality of the putative Δ6-desaturase in the procyclic and bloodstream forms of <i>Trypanosoma brucei</i>DOI 10.1101/2023.11.23.568515
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