Article

Towards reliable quantification of cell state velocities

2022-03-19

Abstract excerpt

A few years ago, it was proposed to use the simultaneous quantification of unspliced and spliced messenger RNA (mRNA) to add a temporal dimension to high-throughput snapshots of single cell RNA sequencing data. This concept can yield additional insight into the transcriptional dynamics of the biological systems under study. However, current methods for inferring cell state velocities from such data (known as RNA v...

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Literature Corpus work: db816663-19dc-5a6a-bf19-3463643eb0eb
DOI: 10.1101/2022.03.17.484754

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