Article

Co-opting regulation bypass repair (CRBR) as a gene correction strategy for monogenic diseases

2020-12-19

Abstract excerpt

With the development of CRISPR/Cas9-mediated gene editing technologies, correction of disease- causing mutations has become possible. However, current gene correction strategies preclude mutation repair in post-mitotic cells of human tissues, and a unique repair strategy must be designed and tested for each and every mutation that may occur in a gene. We have developed a novel gene correction strategy, Co-opting R...

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Literature Corpus work: 8e9f1043-19a3-58e7-b57d-4738be5696db
DOI: 10.1101/2020.12.17.423314

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