Challenges of Gene Editing Therapies for Genodermatoses.

Abstract excerpt

Genodermatoses encompass a wide range of inherited skin diseases, many of which are monogenic. Genodermatoses range in severity and result in early-onset cancers or life-threatening damage to the skin, and there are few curative options. As such, there is a clinical need for single-intervention treatments with curative potential. Here, we discuss the nascent field of gene editing for the treatment of...

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• Genetic Therapy
• Mutation
• Recombinational DNA Repair
• CRISPR-Cas Systems
• Gene Editing