Article

Pharmacological Characterization of Cannabinoid CB2 Receptor Ligands in an In Vitro Model of Resting Microglia

2026-07-28

Abstract excerpt

Microglia are key regulators of central nervous system homeostasis and neuroinflammation, with cannabinoid type 2 receptors (CB2Rs) proposed as important modulators of microglial phenotype and function. This study investigated the pharmacological properties of several CB2R ligands in resting BV2 microglial cells using [35S]GTPγS binding and forskolin-stimulated cAMP assays. Classical CB2R agonists (CP 55,940, WIN...

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Literature Corpus work: 8e939cbe-adbb-596c-a6bb-c44c454d3c5d
DOI: 10.20944/preprints202607.2035.v1

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