Article

Diminished LAG3+ B cells correlate with exacerbated rheumatoid arthritis

2022-10-31

Abstract excerpt

<h4>Background: </h4> Regulatory B (Breg) cells negatively regulate immunity, and the impairment of Breg cells participates in the pathogenesis of rheumatoid arthritis (RA). Lymphocyte activation gene-3 (LAG3) is an inhibitory receptor involved in maintaining immune tolerance. LAG3 + B cells have been identified as a novel regulatory B cell subset. Nevertheless, its role in RA remains elusive. Methods Peripheral...

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Literature Corpus work: 8e4f33df-bd8e-5b03-9fac-597febec38e7
DOI: 10.21203/rs.3.rs-2206383/v1

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