Article
Regulatory B cell: New member of immunosuppressive cell club.
Human immunology - 1 Sept 2015
Ding Tingting, Yan Fan, Cao Shui, Ren Xiubao
Abstract excerpt
Historically, the pivotal role of B cells or B lymphocytes in immunity has been attributed to the production of antibodies. They were also demonstrated to present antigens to T cells and to secrete cytokines, thereby acting as positive regulators in immune responses. A series of studies on autoimmune diseases, however, led researchers to find a unique subset of B cells, later described as "regulatory B cells"...
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