Article

HPK1 inhibitor enhanced tumor response to anti-PD-1 immunotherapy in Non-Hodgkin lymphoma

2022-08-30

Abstract excerpt

Anti-PD-1 immunotherapy has been widely applied in patients with some types of lymphomas. The classical Hodgkin's lymphoma is highly sensitive to immunotherapy but Non-Hodgkin's lymphoma (NHL) is not good response. Therefore, it is valuable to optimize PD-1 blockade treatment in NHL patients. Studies indicated that HPK1 suppressed T cells and reduced the anti-tumor immunity. Therefore, HPK1 inhibitor may restore a...

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Literature Corpus work: b2d3d106-d74b-5716-a150-fdc5a0ed6a4c
DOI: 10.21203/rs.3.rs-1951261/v1

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