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Long non-coding RNA NORAD serves as a promoter of oncogenesis and inhibits ferroptosis via miR-144-3p-mTOR-ferritinophagy axis in cancer

4 Aug 2025

Abstract excerpt

Non-coding RNA activated by DNA damage (NORAD) has been found to enhance proliferation and metastasis of cancer cells. Ferroptosis is characterized by excess lipid peroxidation and has been confirmed to eliminate cancer cells. However, the specific role of NORAD in cancer and ferroptosis is not clear. In this study, data from public databases were downloaded to investigate role of NORAD in cancer. NORAD...

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PMID: 40760677
DOI: 10.1186/s40001-025-02998-2

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