Article
Genotype-Phenotype Correlation of Β-Globin Mutations and Hematological Parameters in Iraqi Β-Thalassemia Patients.
Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology - 31 Jul 2026
Jasim Hamsa Ahmed, Mohammed Hind Adnan, Al-Omairi Raghda
Abstract excerpt
BACKGROUND/AIMS: β-Thalassemia is a common hemoglobin disorder distributed worldwide and caused by mutations in the HBB gene that reduce or abolish β-globin chain synthesis, resulting in chronic hemolytic anemia, ineffective erythropoiesis, and variable clinical severity. Although the molecular spectrum of β-thalassemia has been extensively investigated, data correlating β-globin mutations with hematological...
Topics
- Humans
- Female
- beta-Thalassemia
- Adult
- Male
- beta-Globins
- Adolescent
- Mutation
- Middle Aged
- Young Adult
- Cross-Sectional Studies
- Iraq
- Genetic Association Studies
- Aged
- Fetal Hemoglobin
- Ferritins
- Phenotype
- Iron