Article

Identification of a Novel<i>SLC2A9</i>Gene Association with LDL-C levels and Evaluation of Polygenic Scores in a Multi-Ancestry Genome Wide Association Study

2024-07-07

Abstract excerpt

The genetic determinants of low-density lipoprotein cholesterol (LDL-C) levels in blood have been predominantly explored in European populations and remain poorly understood in Middle Eastern populations. We investigated the genetic architecture of LDL-C variation in the Middle Eastern population of Qatar. Whole genome sequencing data of 13,701 individuals (discovery; n=5939, replication; n=7762) from the populati...

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Literature Corpus work: 8dc70a72-66d1-56b0-be8c-dd4279d608b8
DOI: 10.1101/2024.07.04.24309936

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