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Article

Assessing the genetic burden of familial hypercholesterolemia in a large middle eastern biobank.

Journal of translational medicine - 3 Nov 2022

Gandhi Geethanjali Devadoss, Aamer Waleed, Krishnamoorthy Navaneethakrishnan, Syed Najeeb, Aliyev Elbay, Al-Maraghi Aljazi, Kohailan Muhammad, Alenbawi Jamil, Elanbari Mohammed, Mifsud Borbala, Mokrab Younes, Abi Khalil Charbel, Fakhro Khalid A

Abstract excerpt

BACKGROUND: The genetic architecture underlying Familial Hypercholesterolemia (FH) in Middle Eastern Arabs is yet to be fully described, and approaches to assess this from population-wide biobanks are important for public health planning and personalized medicine. METHODS: We evaluate the pilot phase cohort (n = 6,140 adults) of the Qatar Biobank (QBB) for FH using the Dutch Lipid Clinic Network (DLCN) criteria,...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 36329474
DOI: 10.1186/s12967-022-03697-w
PMCID: PMC9635206

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