Article

Maladaptive striatal plasticity and abnormal reward-learning in cervical dystonia

2019-02-08

Abstract excerpt

In monogenetic generalized forms of dystonia, in vitro neurophysiological recordings have demonstrated direct evidence for abnormal plasticity at the level of the cortico-striatal synapse. It is unclear whether similar abnormalities contribute to the pathophysiology of cervical dystonia, the most common type of focal dystonia. We investigated whether abnormal cortico-striatal synaptic plasticity contributes to ab...

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Literature Corpus work: 8d8f996f-92ed-5043-8a9d-080fe2ada457
DOI: 10.1101/543678

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