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Article

Loss of topographic specificity of LTD-like plasticity is a trait marker in focal dystonia.

Neurobiology of disease - 1 May 2011

Weise David, Schramm Axel, Beck Marcus, Reiners Karlheinz, Classen Joseph

Abstract excerpt

In focal hand dystonia, long-term potentiation (LTP) and depression (LTD)-like neuronal plasticity, as assessed by paired associative stimulation (PAS) targeting the hand-associated motor cortex, is enhanced and the topographic organization of plasticity is lost. However, if any of these abnormalities alone is sufficient to cause focal dystonia (FD) remains unknown. Ten patients with cervical dystonia (CD), 9...

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PMID: 21126584
DOI: 10.1016/j.nbd.2010.11.009

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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