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Article

Reinforcement learning and Gilles de la Tourette syndrome: dissociation of clinical phenotypes and pharmacological treatments.

Archives of general psychiatry - 1 Dec 2011

Worbe Yulia, Palminteri Stefano, Hartmann Andreas, Vidailhet Marie, Lehéricy Stéphane, Pessiglione Mathias

Abstract excerpt

CONTEXT: Gilles de la Tourette syndrome (GTS) is a hyperkinetic movement disorder with heterogeneous phenotypic expression ranging from simple motor and vocal tics to more complex tics associated with psychiatric comorbidities. The heterogeneity of clinical phenotypes may relate to the dysfunction of distinct frontal cortex-basal ganglia circuits. OBJECTIVES: To assess the hypothesis that simple motor tics and...

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Identifiers

PMID: 22147843
DOI: 10.1001/archgenpsychiatry.2011.137

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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