Article

Primed to resolve: A single cell atlas of the shoulder capsule reveals a cellular basis for resolving inflammatory fibrosis

2023-01-16

Abstract excerpt

<h4>ABSTRACT</h4> Fibrotic conditions are a significant global disease burden. While some therapies delay disease progression, none reverse fibrosis. To gain insights into how fibrosis might resolve, we developed a comparative single cell atlas of frozen shoulder capsule tissue; a chronic inflammatory fibrotic human disease that resolves spontaneously. We identified both a population of pro-inflammatory MERTK lo...

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Literature Corpus work: 8d83e6d6-3cad-592d-bae6-fcec126c9dcb
DOI: 10.1101/2023.01.16.522218

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