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Single-cell RNA sequencing reveals distinct immunology profiles in human keloid

3 Aug 2022

Abstract excerpt

Keloids, characterized by skin fibrosis and excessive accumulation of extracellular matrix, remain a therapeutic challenge. In this study, we systematically capture the cellular composition of keloids by the single-cell RNA sequencing technique. Our results indicated that there are significant differences in most cell types present between 12 pairs of keloid and adjacent normal tissue. We found that fibroblasts,...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 35990663
DOI: 10.3389/fimmu.2022.940645

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