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Article

Single-cell transcriptomic analysis of endometriosis provides insights into fibroblast fates and immune cell heterogeneity

7 Jul 2021

Abstract excerpt

BACKGROUND: Endometriosis is an oestrogen-dependent disease with an unclear aetiology and pathogenesis affecting 6-10% of the global female population, predominantly those of reproductive age. Herein, we profile the transcriptomes of approximately 55,000 single cells from three groups including ectopic endometrium, eutopic endometrium from women with endometriosis, and eutopic endometrium from healthy women to...

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PMID: 34233737
DOI: 10.1186/s13578-021-00637-x

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