Article

Single-cell RNA-seq analysis reveals aberrant CSF1 expression in disease-causing synovial fibroblasts of pigmented villonodular synovitis

2021-10-01

Abstract excerpt

<h4>Objectives</h4> Although the role of the CSF1/CSF1R axis in pigmented villonodular synovitis (PVNS) has been confirmed, the cells that express CSF1 and CSF1R and the underlying mechanism remain unclear. Single-cell RNA sequencing (scRNA-seq) of PVNS obtained through biopsies depicted the cellular diversity of PVNS, revealed specific CSF1/CSF1R-expressing cells and further identified novel gene expression that...

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Literature Corpus work: 26360e92-ce2a-5e0d-a6b1-1d77af7105f8
DOI: 10.1101/2021.09.29.462128

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