Article

NKG2D signaling regulates IL-17A-producing γδT cells to promote cancer progression

2021-08-27

Abstract excerpt

γδT cells are unconventional T cells particularly abundant in mucosal tissues that play an important role in tissue surveillance and homeostasis. γδT cell activation is mediated by the T cell receptor composed of γ and δ chains, as well as activating receptors for stress-induced ligands, such as NKG2D. Contrary to the well-established anti-tumor function of γδT cells, recent studies have shown that γδT cells can p...

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Literature Corpus work: 8d76a355-3b27-5772-9e9d-2685e4889556
DOI: 10.1101/2021.08.26.457761

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