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Article

STK11 mutation affects the killing effect of NK cells to promote the progression of lung adenocarcinoma.

APMIS : acta pathologica, microbiologica, et immunologica Scandinavica - 1 Nov 2022

Huang Yun, Zhang Hui, Feng Juan, Tang Bo

Abstract excerpt

STK11 is a frequently mutated tumor suppressor in lung adenocarcinoma (LUAD). STK11 mutations also lead to dramatic changes in the tumor microenvironment. Studies have shown that strengthening the killing effect of NK cells is vital for effective cancer treatment. Nonetheless, the mechanism of STK11 mutation in modulating the killing effect of NK cells on LUAD cells remains unclear. The expression of STK11, Ki67,...

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Share to Adenocarcinoma of Lung
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Gene Expression Regulation, Neoplastic

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Identifiers

PMID: 35988018
DOI: 10.1111/apm.13271

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026.

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