Article

Genetic adaptation to pathogens and increased risk of inflammatory disorders in post-Neolithic Europe

2022-07-03

Abstract excerpt

<h4>ABSTRACT</h4> Ancient genomics can directly detect human genetic adaptation to environmental cues. However, it remains unclear how pathogens have exerted selective pressures on human genome diversity across different epochs and affected present-day inflammatory disease risk. Here, we use an ancestry-aware approximate Bayesian computation framework to estimate the nature, strength, and time of onset of selecti...

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Literature Corpus work: 8d502d43-5003-5412-9e17-1746220e76f2
DOI: 10.1101/2022.07.02.498543

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