The selection landscape and genetic legacy of ancient Eurasians.

doi:10.1038/s41586-023-06705-1

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Article

The selection landscape and genetic legacy of ancient Eurasians.

Nature - 1 Jan 2024

Irving-Pease Evan K, Refoyo-Martínez Alba, Barrie William, Ingason Andrés, Pearson Alice, Fischer Anders, Sjögren Karl-Göran, Halgren Alma S, Macleod Ruairidh, Demeter Fabrice, Henriksen Rasmus A, Vimala Tharsika, McColl Hugh, Vaughn Andrew H, Speidel Leo, Stern Aaron J, Scorrano Gabriele, Ramsøe Abigail, Schork Andrew J, Rosengren Anders, Zhao Lei, Kristiansen Kristian, Iversen Astrid K N, Fugger Lars, Sudmant Peter H, Lawson Daniel J, Durbin Richard, Korneliussen Thorfinn, Werge Thomas, Allentoft Morten E, Sikora Martin, Nielsen Rasmus, Racimo Fernando, Willerslev Eske

Abstract excerpt

The Holocene (beginning around 12,000 years ago) encompassed some of the most significant changes in human evolution, with far-reaching consequences for the dietary, physical and mental health of present-day populations. Using a dataset of more than 1,600 imputed ancient genomes1, we modelled the selection landscape during the transition from hunting and gathering, to farming and pastoralism across West Eurasia....

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Humans
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Alzheimer Disease
Asia
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Europe

European People

Farmers

Genetic Loci

Genetic Predisposition to Disease

Genome, Human

History, Ancient

Human Migration

Hunting

Multigene Family

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PMID: 38200293
DOI: 10.1038/s41586-023-06705-1
PMCID: PMC10781624

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