Article

Presenilin and APP regulate synaptic kainate receptors

2022-02-03

Abstract excerpt

Kainate receptors (KARs) form a family of ionotropic glutamate receptors which regulate the activity of neuronal networks by both pre- and post-synaptic mechanisms. Their implication in pathologies is well documented for epilepsy. The higher prevalence of epileptic symptoms in Alzheimer disease (AD) patients questions the role of KARs in AD. Here we investigated whether the synaptic expression and function of KARs...

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Literature Corpus work: 8d402eb8-64a0-5e9d-90cf-6749cb35d8ab
DOI: 10.1101/2022.02.03.478926

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