Article

Epigenetic heterogeneity after <i>de novo</i> assembly of native full-length Hepatitis B Virus genomes

2020-05-30

Abstract excerpt

Hepatitis B Virus (HBV) is a 3.2KB DNA virus that causes acute and chronic hepatitis. HBV infection is a world health problem, with 350 million chronically infected people at increased risk of developing liver disease and hepatocellular carcinoma (HCC). Methylation of HBV DNA in a CpG context (5mCpG) can alter the expression patterns of viral genes related to infection and cellular transformation. Moreover, it may...

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Literature Corpus work: 8d31ece7-ae1f-5b3d-9078-5abde49c4a08
DOI: 10.1101/2020.05.29.122259

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