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Modeling breast cancer by grafting patient tumor samples in the avian embryo: an <i>in vivo</i> platform for therapy evaluation coupled to large scale molecular analyses

2021-04-27

Abstract excerpt

Lack of preclinical patient-derived xenograft (PDX) cancer models in which to conduct large scale molecular studies seriously impairs the development of effective personalized therapies. We report here on an in vivo concept consisting of implanting human tumor cells in targeted tissues of an avian embryo, delivering therapeutics, evaluating their efficacy by measuring tumors using light sheet confocal microscopy,...

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Literature Corpus work
8d14b289-c3a4-575f-ad6a-41ae7790d8bf
DOI
10.1101/2021.04.26.441511
Open publication

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Modeling breast cancer by grafting patient tumor samples in the avian embryo: an <i>in vivo</i> platform for therapy evaluation coupled to large scale molecular analysesDOI 10.1101/2021.04.26.441511
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