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Article

Association Between Brain Structure and Alcohol Use Behaviors in Adults: A Mendelian Randomization and Multiomics Study.

JAMA psychiatry - 1 Sept 2022

Mavromatis Lucas A, Rosoff Daniel B, Cupertino Renata B, Garavan Hugh, Mackey Scott, Lohoff Falk W

Abstract excerpt

Importance: Past studies have identified associations between brain macrostructure and alcohol use behaviors. However, identifying directional associations between these phenotypes is difficult due to the limitations of observational studies. Objective: To use mendelian randomization (MR) to identify directional associations between brain structure and alcohol use and elucidate the transcriptomic and cellular...

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Identifiers

PMID: 35947372
DOI: 10.1001/jamapsychiatry.2022.2196
PMCID: PMC9366661

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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