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Integrated metabolomics and genetic analyses reveal loss of protective docosahexaenoic acid as a key driver linking ultra-processed food to Crohn’s disease risk

2026-02-22

Abstract excerpt

<h4>Objectives</h4> To characterize ultra-processed food (UPF) circulating metabolic signatures associated with Crohn’s disease (CD) and to localize key metabolic mediators linking UPF intake to CD risk. <h4>Design</h4> Prospective cohort study. <h4>Setting</h4> Two large multi-center cohorts (UK Biobank [UKB] and Whitehall II [WHII] study) across the UK and an Eastern multi-center cohort ONE-IBD Study from Chi...

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Literature Corpus work
8cc1fb95-55fa-5e8d-bc34-73e57ce82c6e
DOI
10.64898/2026.02.20.26346727
Open publication

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Integrated metabolomics and genetic analyses reveal loss of protective docosahexaenoic acid as a key driver linking ultra-processed food to Crohn’s disease riskDOI 10.64898/2026.02.20.26346727
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