Article

ReALLEN: structural variation discovery in cancer genome by sensitive analysis of single-end reads

2018-12-26

Abstract excerpt

<h4>Background</h4> The structural abnormalities in chromosomes are important issues in cancer genomics. Next generation sequencing technologies have big potentials to detect the structural variations precisely and comprehensively. Nevertheless, it is still difficult problem to detect large structural variations from short read sequence data. Major efforts have been achieved with paired-end reads, since discordan...

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Literature Corpus work: 8c581a43-02fd-57d4-8a18-948d164fc688
DOI: 10.1101/506329

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