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Spatial memory training reverses GirK channels modulation in the transgenic APP <sub>Sw,Ind</sub> Alzheimer’s disease mouse model

2022-05-20

Abstract excerpt

Alzheimer’s disease (AD) is a dementia characterized by progressive memory decline and neurodegeneration caused by the accumulation of amyloid-β (Aβ) peptides. Last findings point to an imbalance between excitatory and inhibitory neurotransmission as the initial impairment in early stages, and the hippocampus as one of the most susceptible brain areas. The G-protein-gated inwardly rectifying potassium (GirK) chann...

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Literature Corpus work
8c1f8cc7-3ec3-5541-955b-c63f3d2c8258
DOI
10.1101/2022.05.20.492780
Open publication

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Spatial memory training reverses GirK channels modulation in the transgenic APP <sub>Sw,Ind</sub> Alzheimer’s disease mouse modelDOI 10.1101/2022.05.20.492780
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