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Linobectide: a mathematical-chemistry modified black-hole algorithmic framework for ORF1p inhibitor design

2026-05-08

Abstract excerpt

Computer-aided drug design for conditional biomolecular interfaces requires evaluation across more than one receptor structure, docking pose, or scalar score. LINE-1 ORF1p is treated here as a state-family interface target whose relevant behavior is distributed across receptor microstates, assembly-compatible contact neighborhoods, ligand conformers, and perturbation snapshots. This article presents Linobectide as...

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Literature Corpus work
8c1f0f3c-bba1-574e-92f1-3e088c3417e2
DOI
10.64898/2026.05.06.723314
Open publication

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Linobectide: a mathematical-chemistry modified black-hole algorithmic framework for ORF1p inhibitor designDOI 10.64898/2026.05.06.723314
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