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INP-Guided Network Pharmacology Discloses Multi-Target Therapeutic Strategy Against Cytokine and IgE Storms in the SARS-CoV-2 NB.1.8.1 Variant

2025-06-05

Abstract excerpt

<title>Abstract</title> <p>The continuous development of SARS-CoV-2 has given rise to the NB1.8.1 variant, which exhibits augmented pathogenicity, immune escape, and drug resistance against traditional therapeutics. The current study investigates a multi-layered systems pharmacology approach for identifying new therapeutic candidates that act on both viral entry and host-mediated inflammatory storms. By combining...

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Literature Corpus work
54cca281-ac75-53fa-a1ef-554a0f88055c
DOI
10.21203/rs.3.rs-6819274/v1
Open publication

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INP-Guided Network Pharmacology Discloses Multi-Target Therapeutic Strategy Against Cytokine and IgE Storms in the SARS-CoV-2 NB.1.8.1 VariantDOI 10.21203/rs.3.rs-6819274/v1
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