Article

FastCCC: A permutation-free framework for scalable, robust, and reference-based cell-cell communication analysis in single cell transcriptomics studies

2025-01-29

Abstract excerpt

Detecting cell-cell communications (CCCs) in single-cell transcriptomics studies is fundamental for understanding the function of multicellular organisms. Here, we introduce FastCCC, a permutation-free framework that enables scalable, robust, and reference-based analysis for identifying critical CCCs and uncovering biological insights. FastCCC relies on fast Fourier transformation-based convolution to compute p -...

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Literature Corpus work: 1ddb8eee-3135-5503-aec9-f992c4f94e0a
DOI: 10.1101/2025.01.27.635115

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