Article

Spatially resolved transcriptomic profiling of degraded and challenging fresh frozen samples

2022-09-15

Abstract excerpt

Spatially resolved transcriptomics (SRT) has enabled precise genome-wide mRNA expression profiling within tissue sections. The performance of unbiased SRT methods targeting the polyA tail of mRNA, relies on the availability of specimens with high RNA quality. Moreover, the high cost of currently available SRT assays requires a careful sample screening process to increase the chance of obtaining high-quality data....

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Literature Corpus work: 8bf014d3-9d5a-5da6-9481-f101a788944d
DOI: 10.1101/2022.09.13.507728

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