Article

Dissecting crosstalk induced by cell-cell communication using single-cell transcriptomic data

2025-06-03

Abstract excerpt

During cell-cell communication (CCC), pathways activated by different ligand-receptor pairs may have crosstalk with each other. While multiple methods have been developed to infer CCC networks and their downstream response using single-cell RNA-seq data (scRNA-seq), the potential crosstalk between pathways connecting CCC with its downstream targets has been ignored. Here we introduce a machine learning-based metho...

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Literature Corpus work: 8bc49c7a-3d1e-517a-a0f5-88422bad9245
DOI: 10.1101/2025.05.31.657197

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