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CrossTalkeR: analysis and visualization of ligand–receptorne tworks

11 May 2021

Abstract excerpt

MOTIVATION: Ligand-receptor (LR) network analysis allows the characterization of cellular crosstalk based on single cell RNA-seq data. However, current methods typically provide a list of inferred LR interactions and do not allow the researcher to focus on specific cell types, ligands or receptors. In addition, most of these methods cannot quantify changes in crosstalk between two biological phenotypes. RESULTS:...

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PMID: 35032393
DOI: 10.1093/bioinformatics/btab370

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