Article

NR4A3 is oxidative stress responsible transcription factor through HMOX1, and also controls cell cycle through CCNE1 and CDK2 in pancreatic islet derived 1.1B4 cells

2021-08-20

Abstract excerpt

<h4>ABSTRACT</h4> The mechanism of antioxidant defense system is still controversial. As islet ß-cell is weak in oxidative condition, that causes diabetes mellitus, therefore, antioxidant defense system of human pancreatic islet derived 1.1B4 cell was analyzed. Cells were exposed to H 2 O 2 and comprehensive gene expression was analyzed by Agilent human microarray. HMOX1 and NR4A3 , member of orphan receptor,...

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Literature Corpus work: 8badd248-a73a-5551-9bd4-5a25ed42e55c
DOI: 10.1101/2021.08.20.457070

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