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Life and maladies in the grey area between the up & down regulation of GATA6: Uncharted spots of beta-pancreatic islet cells.

2023-07-14

Abstract excerpt

<title>Abstract</title> <p>Death and dysfunctionality of pancreatic islet beta-cells are a centric key element in the pathogenesis of type 2 diabetes mellitus (T2DM). Saturated fatty acids are commonly circulated in diabetic and obese individuals. Elevated and chronic exposure to fatty acids has a pernicious influence on islet cells’ functionality and survival due to its capability to induce apoptosis and endopla...

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Literature Corpus work
27168c55-939c-5c78-baa2-8449c2029950
DOI
10.21203/rs.3.rs-3161563/v1
Open publication

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