Back to search

Article

Recovery of infectious Oz virus from cloned cDNA

2025-11-12

Abstract excerpt

Oz virus (OZV) is a tick-borne, six-segmented, negative-strand RNA virus in the genus Thogotovirus , family Orthomyxoviridae . A fatal human infection was reported in Japan in 2023. In this study, we established a reverse genetics system to generate infectious recombinant OZV. Six plasmids encoding the full-length OZV genome segments under a murine RNA polymerase I promoter, together with four plasmids expressin...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work
8b311938-f250-5329-a82c-487c60286191
DOI
10.1101/2025.11.12.687958
Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest
Interactive article relationship graphSelect a related publication card to move it into the centre and load its closest explainable connections. Solid lines are source-backed structured connections. Dashed lines are semantic discovery signals and are not scientific evidence.
Recovery of infectious Oz virus from cloned cDNADOI 10.1101/2025.11.12.687958
Segment-specific promoter activity for RNA synthesis in the genome of Oz virus, genus <i>Thogotovirus</i>Semantic proximity
Developments in Negative-Strand RNA Virus Reverse GeneticsSemantic proximity
A decade after the generation of a negative-sense RNA virus from cloned cDNA – what have we learned?Semantic proximity
Development of an entirely plasmid-based reverse genetics system for 12-segmented double-stranded RNA viruses.Semantic proximity
Reverse genetics system for Tick-borne encephalitis virus using Circular Polymerase Extension ReactionSemantic proximity
Production of Novel Ebola Virus-Like Particles from cDNAs: an Alternative to Ebola Virus Generation by Reverse GeneticsSemantic proximity
Vesicular Stomatitis Virus: From Agricultural Pathogen to Vaccine VectorSemantic proximity
Development of a reverse genetics system for Getah virus and characterization of rescued strainsSemantic proximity
The Molecular Biology of Frog Virus 3 and other Iridoviruses Infecting Cold-Blooded VertebratesSemantic proximity
Establishment of a reverse genetics system for Schmallenberg virus, a newly emerged orthobunyavirus in EuropeSemantic proximity
Construction and characterization of a full-length infectious clone of Getah virus in vivoSemantic proximity
Reverse Genetics for Mammalian Orthoreovirus.Semantic proximity
Select a neighboring publication to make it the new centre.