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Establishment of a reverse genetics system for Schmallenberg virus, a newly emerged orthobunyavirus in Europe

20 Dec 2012

Abstract excerpt

Schmallenberg virus (SBV) is a newly emerged orthobunyavirus that has caused widespread disease in cattle, sheep and goats in Europe. Like other orthobunyaviruses, SBV is characterized by a tripartite negative-sense RNA genome that encodes four structural and two non-structural proteins. This study showed that SBV has a wide in vitro host range, and that BHK-21 cells are a convenient host for both SBV propagation...

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PMID: 23255627
DOI: 10.1099/vir.0.049981-0

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