Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Production of Novel Ebola Virus-Like Particles from cDNAs: an Alternative to Ebola Virus Generation by Reverse Genetics

23 Dec 2003

Abstract excerpt

We established a plasmid-based system for generating infectious Ebola virus-like particles (VLPs), which contain an Ebola virus-like minigenome consisting of a negative-sense copy of the green fluorescent protein gene. This system produced nearly 10(3) infectious particles per ml of supernatant, equivalent to the titer of Ebola virus generated by a reverse genetics system. Interestingly, infectious Ebola VLPs...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Viral gastroenteritis research and epidemiology
Share to Viral Infections and Outbreaks Research
Share to Virus-based gene therapy research

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Source

Identifiers

PMID: 14694131
DOI: 10.1128/jvi.78.2.999-1005.2004

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Production of Novel Ebola Virus-Like Particles from cDNAs: an Alternative to Ebola Virus Generation by Reverse GeneticsPMID 14694131Read ↗

A Novel Life Cycle Modeling System for Ebola Virus Shows a Genome Length-Dependent Role of VP24 in Virus InfectivitySemantic proximity Read ↗

Modeling The Lifecycle Of Ebola Virus Under Biosafety Level 2 Conditions With Virus-like Particles Containing Tetracistronic MinigenomesSemantic proximity Read ↗

Generation of biologically contained Ebola virusesSemantic proximity Read ↗

Recombinant Lloviu virus as a model to study inaccessible zoonotic virusesSemantic proximity Read ↗

Recombinant Lloviu virus as a tool to study viral replication and host responsesSemantic proximity Read ↗

Flavivirus reverse genetic systems, construction techniques and applications: A historical perspectiveSemantic proximity Read ↗

RNA Polymerase I-Driven Minigenome System for Ebola VirusesSemantic proximity Read ↗

A decade after the generation of a negative-sense RNA virus from cloned cDNA – what have we learned?Semantic proximity Read ↗

Negative-strand RNA viruses: genetic engineering and applications.Semantic proximity Read ↗

Plasmid-Driven Formation of Influenza Virus-Like ParticlesSemantic proximity Read ↗

Developments in Negative-Strand RNA Virus Reverse GeneticsSemantic proximity Read ↗

Production of single-round infectious chimeric flaviviruses with DNA-based Japanese encephalitis virus repliconSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.