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Reliability of H3K27M Detection Using a Commercially Available Blood-based Comprehensive Genomic Profiling Test in Patients with Diffuse Midline Gliomas: Analysis of the Nationwide C- CAT Database in Japan

2025-11-07

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<title>Abstract</title> <p>Purpose This study aimed to assess the ability of FoundationOne Liquid CDx (F1 Liquid), a blood-based comprehensive genomic profiling test introduced in Japan in 2021, to detect the H3K27M mutation in patients with diffuse midline glioma using a nationwide database in Japan. Methods We identified patients with IDH-wildtype diffuse gliomas in midline locations registered in the Center fo...

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Literature Corpus work: 8b2589ad-f3c2-5745-a656-e26369b9a842
DOI: 10.21203/rs.3.rs-7932452/v1

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