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Article

Nationwide genomic data analysis of central nervous system tumors in Japan based on C-CAT database.

International journal of clinical oncology - 1 Jul 2026

Kawauchi Daisuke, Ohno Makoto, Takahashi Masamichi, Koyama Takafumi, Sunami Kuniko, Hirata Makoto, Yanagisawa Shunsuke, Omura Takaki, Aoki Takuma, Fujii Genta, Saito Koji, Yamamoto Tetsuya, Suzuki Hiromichi, Narita Yoshitaka

Abstract excerpt

BACKGROUND: Comprehensive genomic profiling test (CGPT) using next-generation sequencing (NGS) plays a vital role in cancer diagnosis, treatment option, and prognostic evaluation. In Japan, three tissue-based CGPTs, FoundationOne® CDx, GenMineTOP, and NCC OncoGuide™, are reimbursed under public health insurance. However, their comparative performance in central nervous system (CNS) tumors remains unclear....

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 42089945
DOI: 10.1007/s10147-026-03031-0

Genes

BRAF
BRCA2
CAT
EGFR
FGFR3
KIAA1549
MET
MSH6
PTPRZ1
TACC3
TP53

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026.

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