Article

Using Extracellular miRNA Signatures to Identify Patients with LRRK2-Related Parkinson’s Disease

2023-11-07

Abstract excerpt

<h4>Background</h4> Mutations in the Leucine Rich Repeat Kinase 2 gene are highly relevant in both sporadic and familial cases of Parkinson’s disease. Specific therapies are entering clinical trials but patient stratification remains challenging. Dysregulated microRNA expression levels have been proposed as biomarker candidates in sporadic Parkinson’s disease. <h4>Objective</h4> In this proof-of concept study we...

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Literature Corpus work: 8b16f1db-fc83-5a5a-a0fa-3147d990d63a
DOI: 10.1101/2023.11.06.565815

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