Article
Hypothesis: Do miRNAs Targeting the Leucine-Rich Repeat Kinase 2 Gene (LRRK2) Influence Parkinson's Disease Susceptibility?
Omics : a journal of integrative biology - 1 Apr 2016
Yılmaz Şenay Görücü, Geyik Sırma, Neyal Ayşe Münife, Soko Nyarai D, Bozkurt Hakan, Dandara Collet
Abstract excerpt
Parkinson's disease (PD) is a frequently occurring neurodegenerative motor disorder adversely impacting global health. There is a paucity of biomarkers and diagnostics that can forecast susceptibility to PD. A new research frontier for PD pathophysiology is the study of variations in microRNA (miRNA) expression whereby miRNAs serve as "upstream regulators" of gene expression in relation to functioning of the...
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