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Article

Impact of Pharmacogenetics on Efficacy and Safety of Statin Therapy for Dyslipidemia

3 Jul 2017

Abstract excerpt

Interindividual variability in response to 3-hydroxy-3-methylglutaryl coenzyme A reductase inhibitors, or statins, with regard to both efficacy and safety is an obvious target for pharmacogenetic research. Many genes have been identified as possible contributors to variability in statin response and safety. Genetic polymorphisms may alter the structure or expression of coded proteins, with potential impacts on...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 28672099
DOI: 10.1002/phar.1981

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