Article

Elevation of miR-302b prevents multiple myeloma cell growth and bone destruction by blocking DKK1 secretion

2021-02-11

Abstract excerpt

<title>Abstract</title> <p><bold>Background: </bold>Myeloma bone disease (MBD) is a severe complication of multiple myeloma (MM) mainly due to an imbalance between enhanced osteoclast activity and reduced osteoblast function. Previous studies have demonstrated that miRNAs play a vital role in the osteogenic differentiation of mesenchymal stromal cells (MSCs) in MM. However, the value of miR‑302b in MBD remains to...

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Literature Corpus work: 8ae558f7-c702-5c9f-b12b-c1083b430224
DOI: 10.21203/rs.3.rs-98086/v2

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