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Article

Downregulation of MicroRNA-152 contributes to high expression of DKK1 in multiple myeloma

23 Sept 2015

Abstract excerpt

Multiple myeloma (MM) induced bone lesion is one of the most crippling characteristics, and the MM secreted Dickkopf-1 (DKK1) has been reported to play important role in this pathologic process. However, the underlying regulation mechanisms involved in DKK1 expression are still unclear. In this study, we validated the expression patterns of microRNA (miR) 15a, 34a, 152, and 223 in MM cells and identified that...

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Identifiers

PMID: 26400224
DOI: 10.1080/15476286.2015.1094600

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