Article

Examining Selection Dynamics and Limitations in Multi-round Protein Selection of High Diversity Libraries

2025-11-09

Abstract excerpt

Proteins and peptides underpin essential biological functions and technological applications, from targeting disease-relevant interactions to providing broad enzymatic activities. However, engineering molecules with desired properties remains difficult, owing to complex sequence-structure-function relationships and the lack of data on specific systems. Experimental selection strategies, including directed evolutio...

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Literature Corpus work: 8ad3bb47-204c-5892-af6f-ad89685eeab0
DOI: 10.1101/2025.11.09.687419

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