Article

GOT1 inhibits hepatocellular carcinoma progression by regulating SLC25A5-dependent mitochondrial apoptosis

2025-09-18

Abstract excerpt

<title>Abstract</title> <p>Hepatocellular carcinoma (HCC) is the most common subtype of primary liver cancer and carries a poor prognosis, with most patients diagnosed at advanced stages that are unresectable and resistant to targeted therapies. Thus, the identification of novel therapeutic targets remains urgently needed. In this study, we investigated the role of glutamate-oxaloacetate transaminase 1 (GOT1) in...

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Literature Corpus work: 8ac940f6-6169-50fa-9a75-4fc02e4d20ba
DOI: 10.21203/rs.3.rs-7570221/v1

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